abstract：BACKGROUND:Hospitalization burden associated with influenza and respiratory syncytial virus (RSV) is uncertain due to ambiguity in the inference methodologies employed for its estimation. OBJECTIVES:Utilization of a new method to quantitate the above burden. METHODS:Weekly hospitalization rates for several principal ...

journal_title：Influenza and other respiratory viruses

authors： Goldstein E,Greene SK,Olson DR,Hanage WP,Lipsitch M

更新日期：2015-09-01 00:00:00

abstract：INTRODUCTION:Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS:Twenty-six countries in the Southern (n = 5) and Northern (n = 7...

journal_title：Influenza and other respiratory viruses

authors： Caini S,Huang QS,Ciblak MA,Kusznierz G,Owen R,Wangchuk S,Henriques CM,Njouom R,Fasce RA,Yu H,Feng L,Zambon M,Clara AW,Kosasih H,Puzelli S,Kadjo HA,Emukule G,Heraud JM,Ang LW,Venter M,Mironenko A,Brammer L,Mai

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Although it is known that febrile respiratory illnesses (FRI) may be caused by multiple respiratory pathogens, there are no population-level studies describing its impact on clinical disease. METHODS:Between May 2009 and October 2012, 7733 FRI patients and controls in the Singapore military had clinical dat...

journal_title：Influenza and other respiratory viruses

authors： Ho ZJ,Zhao X,Cook AR,Loh JP,Ng SH,Tan BH,Lee VJ

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:Knowledge of the secondary attack rate (SAR) and serial interval (SI) of influenza is important for assessing the severity of seasonal epidemics of the virus. To date, such estimates have required extensive surveys of target populations. Here, we propose a method for estimating the intrafamily SAR and SI fro...

journal_title：Influenza and other respiratory viruses

authors： Yom-Tov E,Johansson-Cox I,Lampos V,Hayward AC

更新日期：2015-07-01 00:00:00

abstract：:As the most important viral cause of severe respiratory disease in infants and increasing recognition as important in the elderly and immunocompromised, respiratory syncytial virus (RSV) is responsible for a massive health burden worldwide. Prophylactic antibodies were successfully developed against RSV. However, thei...

journal_title：Influenza and other respiratory viruses

authors： Broadbent L,Groves H,Shields MD,Power UF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Since 2009, Thailand has recommended influenza vaccine for children aged 6 months through 2 years, but no estimates of influenza vaccine coverage or effectiveness are available for this target group. METHODS:During August 2011-May 2013, high-risk and healthy children aged ≤36 months were enrolled in a 2-yea...

journal_title：Influenza and other respiratory viruses

authors： Kittikraisak W,Suntarattiwong P,Levy J,Fernandez S,Dawood FS,Olsen SJ,Chotpitayasunondh T

更新日期：2015-03-01 00:00:00

abstract：:This study used Poisson regression modelling to estimate influenza-associated mortality in New Zealand for 1990-2008. Inputs were weekly numbers of deaths and influenza and RSV isolates. Seasonal influenza was associated with an average of 401 medical deaths annually from 1990 to 2008, a rate of 10.6 (95% CI: 7.9, 13....

journal_title：Influenza and other respiratory viruses

authors： Kessaram T,Stanley J,Baker MG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Respiratory tract infections are a major cause of outpatient visits, yet only a portion is tested to determine the etiologic organism. Multiplex reverse transcriptase polymerase chain reaction (MRT-PCR) assays for detection of multiple viruses are being used increasingly in clinical settings. METHODS:During...

journal_title：Influenza and other respiratory viruses

authors： Zimmerman RK,Rinaldo CR,Nowalk MP,Gk B,Thompson MG,Moehling KK,Bullotta A,Wisniewski S

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are particularly relevant in influenza vaccine trials in the elderly where reduction in symptom severity could prevent illness-related functional impairment. OBJECTIVES:To evaluate PROs in people aged ≥ 65 years receiving two different vaccines. METHODS:This was a phase III...

journal_title：Influenza and other respiratory viruses

authors： van Essen GA,Beran J,Devaster JM,Durand C,Duval X,Esen M,Falsey AR,Feldman G,Gervais P,Innis BL,Kovac M,Launay O,Leroux-Roels G,McElhaney JE,McNeil S,Oujaa M,Richardus JH,Ruiz-Palacios G,Osborne RH,Oostvogels L

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Nineteen mass vaccination clinics were established in Montreal, Canada, as part of the 2009 influenza A/H1N1p vaccination campaign. Although approximately 50% of the population was vaccinated, there was a considerable variation in clinic performance and community vaccine coverage. OBJECTIVE:To identify comm...

journal_title：Influenza and other respiratory viruses

authors： Charland KM,de Montigny L,Brownstein JS,Buckeridge DL

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Limited data exist on transmission dynamics and effectiveness of control measures for influenza in confined settings. OBJECTIVES:To investigate the transmission dynamics of a 2009 pandemic H1N1 influenza A outbreak aboard a Peruvian Navy ship and quantify the effectiveness of the implemented control measure...

journal_title：Influenza and other respiratory viruses

authors： Vera DM,Hora RA,Murillo A,Wong JF,Torre AJ,Wang D,Boulay D,Hancock K,Katz JM,Ramos M,Loayza L,Quispe J,Reaves EJ,Bausch DG,Chowell G,Montgomery JM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Equine influenza (EI) is a highly contagious respiratory disease of horses. OBJECTIVES:The aim of this study was to evaluate two rapid antigen detection kits (Directigen or DFA, and Espline) and a commercial ELISA for the detection of EI nucleoprotein in nasal swabs. METHOD:Nasal swab samples from naturall...

journal_title：Influenza and other respiratory viruses

authors： Galvin P,Gildea S,Nelly M,Quinlivan M,Arkins S,Walsh C,Cullinane A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The 1918 influenza pandemic caused disproportionately high mortality among certain age groups. The mechanisms underlying these differences are not fully understood. OBJECTIVES:To explore the dynamics of the 1918 pandemic and to identify potential age-specific transmission patterns. METHODS:We examined 1915...

journal_title：Influenza and other respiratory viruses

authors： Yang W,Petkova E,Shaman J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Reviews of the global response to the 2009 pandemic of influenza A/H1N1 affirmed the importance of assessment of preparedness and response capabilities. DESIGN:The U. S. Centers for Disease Control and Prevention (CDC) and partners developed the National Inventory of Core Capabilities for Pandemic Influenza...

journal_title：Influenza and other respiratory viruses

authors： MacDonald G,Moen AC,St Louis ME

更新日期：2014-03-01 00:00:00

abstract：:Within a hand-washing clinical trial, we evaluated factors associated with fomite contamination in households with an influenza-infected child. Influenza virus RNA contamination was higher in households with low absolute humidity and in control households, suggesting that hand washing reduces surface contamination. ...

journal_title：Influenza and other respiratory viruses

authors： Levy JW,Suntarattiwong P,Simmerman JM,Jarman RG,Johnson K,Olsen SJ,Chotpitayasunondh T

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To estimate, using Bayesian evidence synthesis, the age-group-specific annual incidence of symptomatic infection with seasonal influenza in the Netherlands over the period 2005-2007. METHODS:The Netherlands population and age group distribution for 2006 defined the base population. The number of influenza-l...

journal_title：Influenza and other respiratory viruses

authors： McDonald SA,Presanis AM,De Angelis D,van der Hoek W,Hooiveld M,Donker G,Kretzschmar ME

更新日期：2014-01-01 00:00:00

abstract：:Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for ...

journal_title：Influenza and other respiratory viruses

authors： Imamura T,Suzuki A,Lupisan S,Kamigaki T,Okamoto M,Roy CN,Olveda R,Oshitani H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The genetic and antigenic characteristics of influenza A viruses (IAV) within and between species change over time due to antigenic shift and drift. Although pigs are known to play a key role in the epidemiology of IAV between species, little is known about the molecular evolution of IAV hemagglutinin (HA) i...

journal_title：Influenza and other respiratory viruses

authors： Diaz A,Allerson M,Culhane M,Sreevatsan S,Torremorell M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The annual differences in the seasonal influenza vaccine and the circulating strains make it necessary to assess influenza vaccine effectiveness (VE) yearly. We assessed the effectiveness of the trivalent inactivated influenza vaccine for the 2010-2011 and 2011-2012 influenza seasons among children in Guangz...

journal_title：Influenza and other respiratory viruses

authors： Fu C,He Q,Li Z,Xu J,Li Y,Lu J,Li K,Yang Q,Dong Z,Liu X,Wen S,Hu W,Zhang D,Lv J,Zhu W,Wang M

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:To determined the pathogen-specific incidence of respiratory virus infection in Hutterite communities occurring over the 2008-2009 influenza season and assess temporal characteristics of respiratory illness related to infection. METHODS:3273 participants community members enrolled in a cluster randomized tr...

journal_title：Influenza and other respiratory viruses

authors： Kim TH,Russell ML,Fonseca K,Aoki F,Horsman G,Van Caeseele P,Chokani K,Voight M,Babiuk L,Moss L,Webby R,Earn DJ,Singh P,Howse C,Loeb M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Influenza and other respiratory infections cause excess winter morbidity in children. This study assessed the economic impact of influenza-like illness (ILI) on families with children attending childcare using a societal perspective. METHODS:We conducted a prospective cohort study in 90 childcare centres an...

journal_title：Influenza and other respiratory viruses

authors： Yin JK,Salkeld G,Lambert SB,Dierig A,Heron L,Leask J,Yui Kwan Chow M,Booy R

更新日期：2013-11-01 00:00:00

abstract：:Progress in the development of antivirals for non-influenza respiratory viruses has been slow with the result that many unmet medical needs and few approved agents currently exist. This commentary selectively reviews examples of where specific agents have provided promising clinical benefits in selected target populat...

journal_title：Influenza and other respiratory viruses

authors： Hayden FG

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Influenza and respiratory syncytial viruses (RSV) are important viral pathogens in childhood. OBJECTIVES:Our aim was to estimate the effect of influenza and RSV on excess hospitalizations for acute lower respiratory tract infections (ALRTI) in children aged≤5. METHODS:Retrospective, population-based study ...

journal_title：Influenza and other respiratory viruses

authors： Učakar V,Sočan M,Trilar KP

更新日期：2013-11-01 00:00:00

abstract：:We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when c...

journal_title：Influenza and other respiratory viruses

authors： Martin ET,Archer C,McRoberts J,Kulik J,Thurston T,Lephart P,Kaye KS

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:The goal of this double-blind, randomized, controlled clinical trial was to assess the safety and immunogenicity of two different doses of a monovalent split-virion 2009 pandemic influenza A/H1N1 vaccine without adjuvant in Chinese infants aged 6-35 months. DESIGN AND SETTING  Subjects were randomly assigned...

journal_title：Influenza and other respiratory viruses

authors： Li YP,Li W,Liang XF,Liu Y,Huang XC,Li CG,Li RC,Wang JZ,Wang HQ,Yin WD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Highly pathogenic avian influenza A/H5N1 virus remains a potential pandemic threat, and it is essential to continue vaccine development against this subtype. A local mucosal immune response in the upper respiratory tract may stop influenza transmission. It is therefore important to develop effective intranas...

journal_title：Influenza and other respiratory viruses

authors： Svindland SC,Pedersen GK,Pathirana RD,Bredholt G,Nøstbakken JK,Jul-Larsen Å,Guzmán CA,Montomoli E,Lapini G,Piccirella S,Jabbal-Gill I,Hinchcliffe M,Cox RJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:During April-July 2009, U.S. hospitalization rates for 2009 pandemic influenza A (H1N1) virus (H1N1pdm09) infection were estimated at 4·5/100 000 persons. We describe rates and risk factors for H1N1pdm09 infection among American Indians (AIs) in four isolated southwestern U.S. communities served by the India...

journal_title：Influenza and other respiratory viruses

authors： Suryaprasad A,Redd JT,Hancock K,Branch A,Steward-Clark E,Katz JM,Fry AM,Cheek JE,Influenza Serology Working Group.,American Indian and Alaska Native Pandemic Influenza A (H1N1) Investigation Team.

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Vietnam is currently developing domestic capability to manufacture influenza vaccines but information on the genetic and antigenic characteristics of locally circulating seasonal influenza viruses is limited. To assess the relevance of WHO recommended vaccine strains to the situation in Vietnam, we analyzed ...

journal_title：Influenza and other respiratory viruses

authors： Vuong CD,Hoang PM,Nguyen HL,Nguyen HT,Nguyen TC,Le TT,Dennis DT,Kapella BK,Kile JC,Le MQ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Despite the use of vaccines, low-pathogenic (LP) H5N2 influenza viruses have continued to circulate and evolve in chickens in Mexico since 1993, giving rise to multiple genetic variants. Antigenic drift is partially responsible for the failure to control H5N2 influenza by vaccination; the contribution of mat...

journal_title：Influenza and other respiratory viruses

authors： Forrest HL,Garcia A,Danner A,Seiler JP,Friedman K,Webster RG,Jones JC

更新日期：2013-11-01 00:00:00

abstract：:The ID Screen Influenza H5 Antibody Competition enzyme-linked immunosorbent assay was tested for the detection of antibodies to the H5 subtype of influenza A (IA) virus in waterfowl. Assays were conducted with sera obtained from Mallards (Anas platyrhynchos) and Pekin Ducks (Anas platyrhynchos domestica), experimental...

journal_title：Influenza and other respiratory viruses

authors： Lebarbenchon C,Pantin-Jackwood M,Kistler WM,Luttrell MP,Spackman E,Stallknecht DE,Brown JD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Estimating influenza incidence in outpatient settings is challenging. We used outpatient healthcare practice populations as a proxy to estimate community incidence of influenza-like illness (ILI) and laboratory-confirmed influenza-associated ILI. METHODS:From October 2009 to July 2010, 38 outpatient practic...

journal_title：Influenza and other respiratory viruses

authors： Fowlkes A,Dasgupta S,Chao E,Lemmings J,Goodin K,Harris M,Martin K,Feist M,Wu W,Boulton R,Temte J,Brammer L,Finelli L

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interferon alpha (IFNα) is a known antiviral agent. A double-blind, placebo-controlled clinical trial was conducted investigating the use of low-dose oral interferon alpha for preventing acute viral respiratory illnesses. METHODS:Two hundred healthy adults aged 18-75 years were enrolled and co...

journal_title：Influenza and other respiratory viruses

authors： Bennett AL,Smith DW,Cummins MJ,Jacoby PA,Cummins JM,Beilharz MW

更新日期：2013-09-01 00:00:00

abstract：:Highly pathogenic avian influenza A H5N1 viruses remain a significant health threat to humans given the continued rare occurrence of human cases with a high case fatality rate. This brief literature review summarizes available evidence of risk factors for H5N1 infection in humans and updates a recent systematic review...

journal_title：Influenza and other respiratory viruses

authors： Van Kerkhove MD

更新日期：2013-09-01 00:00:00

abstract：:When the influenza A (H1N1) pandemic spread across the globe from April 2009 to August 2010, many WHO Member States used antiviral drugs, specifically neuraminidase inhibitors (NAIs) oseltamivir and zanamivir, to treat influenza patients in critical condition. Antivirals have been found to be effective in reducing sev...

journal_title：Influenza and other respiratory viruses

authors： Miller PE,Rambachan A,Hubbard RJ,Li J,Meyer AE,Stephens P,Mounts AW,Rolfes MA,Penn CR

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Highly pathogenic H5N1 influenza viruses reemerged in humans in 2003 and have caused fatal human infections in Asia and Africa as well as ongoing outbreaks in poultry. These viruses have evolved substantially and are now so antigenically varied that a single vaccine antigen may not protect against all circul...

journal_title：Influenza and other respiratory viruses

authors： Ducatez MF,Webb A,Crumpton JC,Webby RJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Wild birds are the natural hosts for influenza A viruses (IAVs) and provide a niche for the maintenance of this virus. OBJECTIVES:This study was undertaken to analyze nucleotide sequences of the matrix (M) gene of AIVs isolated from wild birds and live bird markets (LBMs) to index the changes occurring in t...

journal_title：Influenza and other respiratory viruses

authors： Chander Y,Jindal N,Sreevatsan S,Stallknecht DE,Goyal SM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Modern molecular techniques reveal new information on the role of respiratory viruses in community-acquired pneumonia. In this study, we tried to determine the prevalence of respiratory viruses and bacteria in patients with community-acquired pneumonia who were admitted to the hospital. METHODS:Between Apri...

journal_title：Influenza and other respiratory viruses

authors： Huijskens EG,van Erkel AJ,Palmen FM,Buiting AG,Kluytmans JA,Rossen JW

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Longitudinal data are limited about the circulating strains of influenza viruses and their public health impact in Indonesia. We conducted influenza surveillance among outpatients and hospitalized patients with influenza-like illness (ILI) across the Indonesian archipelago from 2003 through 2007. METHODOLOG...

journal_title：Influenza and other respiratory viruses

authors： Kosasih H,Roselinda,Nurhayati,Klimov A,Xiyan X,Lindstrom S,Mahoney F,Beckett C,Burgess TH,Blair PJ,Uyeki TM,Sedyaningsih ER

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:At the onset of the pandemic H1N1/09 influenza A outbreak in Australia, health authorities devised official clinical case definitions to guide testing and access to antiviral therapy. OBJECTIVES:To assess the diagnostic accuracy of these case definitions and to attempt to improve on them using a scoring sys...

journal_title：Influenza and other respiratory viruses

authors： Mahony AA,Cheng AC,Olsen KL,Aboltins CA,Black JF,Johnson PD,Lindsay Grayson M,Torresi J

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The relationship between obesity and susceptibility to influenza infection in humans is unclear. Morbidly obese people were at an increased risk of complications from 2009 pandemic H1N1 influenza [A(H1N1)pdm09]. OBJECTIVE:The goal of this study was to determine whether medically attended, laboratory-confirm...

journal_title：Influenza and other respiratory viruses

authors： Coleman LA,Waring SC,Irving SA,Vandermause M,Shay DK,Belongia EA

更新日期：2013-03-01 00:00:00